A liposomal Gd contrast agent does not cross the mouse placental barrier

The trans-placental permeability of liposomal Gadolinium (Gd) nanoparticle contrast agents was evaluated in a pregnant mouse model. Pregnant Balb/c mice at 16.5 (±1) days of gestation were imaged using a 3D Spoiled Gradient Echo method at 9.4 T using two contrast agents: a clinically approved Gd che...

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Detalles Bibliográficos
Autores principales: Shetty, Anil N., Pautler, Robia, Ghagahda, Ketan, Rendon, David, Gao, Haijun, Starosolski, Zbigniew, Bhavane, Rohan, Patel, Chandreshkumar, Annapragada, Ananth, Yallampalli, Chandrasekhar, Lee, Wesley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906290/
https://www.ncbi.nlm.nih.gov/pubmed/27298076
http://dx.doi.org/10.1038/srep27863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906290/
https://www.ncbi.nlm.nih.gov/pubmed/27298076
http://dx.doi.org/10.1038/srep27863

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