Amicoumacin A induces cancer cell death by targeting the eukaryotic ribosome

Amicoumacin A is an antibiotic that was recently shown to target bacterial ribosomes. It affects translocation and provides an additional contact interface between the ribosomal RNA and mRNA. The binding site of amicoumacin A is formed by universally conserved nucleotides of rRNA. In this work, we s...

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Detalles Bibliográficos
Autores principales: Prokhorova, Irina V., Akulich, Kseniya A., Makeeva, Desislava S., Osterman, Ilya A., Skvortsov, Dmitry A., Sergiev, Petr V., Dontsova, Olga A., Yusupova, Gulnara, Yusupov, Marat M., Dmitriev, Sergey E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906347/
https://www.ncbi.nlm.nih.gov/pubmed/27296282
http://dx.doi.org/10.1038/srep27720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906347/
https://www.ncbi.nlm.nih.gov/pubmed/27296282
http://dx.doi.org/10.1038/srep27720

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