Novel high throughput pooled shRNA screening identifies NQO1 as a potential drug target for host directed therapy for tuberculosis

Chemical regulation of macrophage function is one key strategy for developing host-directed adjuvant therapies for tuberculosis (TB). A critical step to develop these therapies is the identification and characterization of specific macrophage molecules and pathways with a high potential to serve as...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Qing, Karim, Ahmad F., Ding, Xuedong, Das, Biswajit, Dobrowolski, Curtis, Gibson, Richard M., Quiñones-Mateu, Miguel E., Karn, Jonathan, Rojas, Roxana E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906352/
https://www.ncbi.nlm.nih.gov/pubmed/27297123
http://dx.doi.org/10.1038/srep27566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906352/
https://www.ncbi.nlm.nih.gov/pubmed/27297123
http://dx.doi.org/10.1038/srep27566

Ejemplares similares