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A multistep continuous flow synthesis machine for the preparation of pyrazoles via a metal-free amine-redox process
A versatile multistep continuous flow setup is reported for the four-step conversion of anilines into pyrazole products. The synthesis machine incorporates the use of amine-redox chemistry through diazotization and a metal-free vitamin C mediated reduction. The machine can be used for the synthesis...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906367/ https://www.ncbi.nlm.nih.gov/pubmed/27398231 http://dx.doi.org/10.1039/c5re00082c |