Joint-specific DNA methylation and transcriptome signatures in rheumatoid arthritis identify distinct pathogenic processes

Stratifying patients on the basis of molecular signatures could facilitate development of therapeutics that target pathways specific to a particular disease or tissue location. Previous studies suggest that pathogenesis of rheumatoid arthritis (RA) is similar in all affected joints. Here we show tha...

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Detalles Bibliográficos
Autores principales: Ai, Rizi, Hammaker, Deepa, Boyle, David L., Morgan, Rachel, Walsh, Alice M., Fan, Shicai, Firestein, Gary S., Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906396/
https://www.ncbi.nlm.nih.gov/pubmed/27282753
http://dx.doi.org/10.1038/ncomms11849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906396/
https://www.ncbi.nlm.nih.gov/pubmed/27282753
http://dx.doi.org/10.1038/ncomms11849

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