Urinary miR-16 transactivated by C/EBPβ reduces kidney function after ischemia/reperfusion–induced injury

Ischemia-reperfusion (I/R) induced acute kidney injury (AKI) is regulated by transcriptional factors and microRNAs (miRs). However, modulation of miRs by transcriptional factors has not been characterized in AKI. Here, we found that urinary miR-16 was 100-fold higher in AKI patients. MiR-16 was dete...

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Detalles Bibliográficos
Autores principales: Chen, Hsi-Hsien, Lan, Yi-Fan, Li, Hsiao-Fen, Cheng, Ching-Feng, Lai, Pei-Fang, Li, Wei-Hua, Lin, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906401/
https://www.ncbi.nlm.nih.gov/pubmed/27297958
http://dx.doi.org/10.1038/srep27945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906401/
https://www.ncbi.nlm.nih.gov/pubmed/27297958
http://dx.doi.org/10.1038/srep27945

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