Cholesterol and ORP1L-mediated ER contact sites control autophagosome transport and fusion with the endocytic pathway

Autophagy is the main homeostatic pathway guiding cytosolic materials for degradation by the lysosome. Maturation of autophagosomes requires their transport towards the perinuclear region of the cell, with key factors underlying both processes still poorly understood. Here we show that transport and...

Descripción completa

Detalles Bibliográficos
Autores principales: Wijdeven, Ruud H., Janssen, Hans, Nahidiazar, Leila, Janssen, Lennert, Jalink, Kees, Berlin, Ilana, Neefjes, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906411/
https://www.ncbi.nlm.nih.gov/pubmed/27283760
http://dx.doi.org/10.1038/ncomms11808

Ejemplares similares

Ejemplares similares