Cinnamide Derivatives of d‐Mannose as Inhibitors of the Bacterial Virulence Factor LecB from Pseudomonas aeruginosa

Pseudomonas aeruginosa is an opportunistic Gram‐negative pathogen with high antibiotic resistance. Its lectin LecB was identified as a virulence factor and is relevant in bacterial adhesion and biofilm formation. Inhibition of LecB with carbohydrate‐based ligands results in a decrease in toxicity an...

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Detalles Bibliográficos
Autores principales: Sommer, Roman, Hauck, Dirk, Varrot, Annabelle, Wagner, Stefanie, Audfray, Aymeric, Prestel, Andreas, Möller, Heiko M., Imberty, Anne, Titz, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906503/
https://www.ncbi.nlm.nih.gov/pubmed/27308201
http://dx.doi.org/10.1002/open.201500162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906503/
https://www.ncbi.nlm.nih.gov/pubmed/27308201
http://dx.doi.org/10.1002/open.201500162

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