Single-stranded DNA library preparation uncovers the origin and diversity of ultrashort cell-free DNA in plasma

Circulating cell-free DNA (cfDNA) is emerging as a powerful monitoring tool in cancer, pregnancy and organ transplantation. Nucleosomal DNA, the predominant form of plasma cfDNA, can be adapted for sequencing via ligation of double-stranded DNA (dsDNA) adapters. dsDNA library preparations, however,...

Descripción completa

Detalles Bibliográficos
Autores principales: Burnham, Philip, Kim, Min Seong, Agbor-Enoh, Sean, Luikart, Helen, Valantine, Hannah A., Khush, Kiran K., De Vlaminck, Iwijn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906518/
https://www.ncbi.nlm.nih.gov/pubmed/27297799
http://dx.doi.org/10.1038/srep27859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906518/
https://www.ncbi.nlm.nih.gov/pubmed/27297799
http://dx.doi.org/10.1038/srep27859

Ejemplares similares