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Validation of an IFNγ/IL2 FluoroSpot assay for clinical trial monitoring

BACKGROUND: The FluoroSpot assay, an advancement of the ELISpot assay, enables simultaneous measurement of different analytes secreted at a single-cell level. This allows parallel detection of several cytokines secreted by immune cells upon antigen recognition. Easier standardization, higher sensiti...

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Detalles Bibliográficos
Autores principales: Körber, Nina, Behrends, Uta, Hapfelmeier, Alexander, Protzer, Ulrike, Bauer, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906590/
https://www.ncbi.nlm.nih.gov/pubmed/27297580
http://dx.doi.org/10.1186/s12967-016-0932-7