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Increased extrasynaptic GluN2B expression is involved in cognitive impairment after isoflurane anesthesia

There is increasing concern regarding the postoperative cognitive dysfunction (POCD) in the aging population, and general anesthetics are believed to be involved. Isoflurane exposure induced increased N-methyl-D-aspartic acid receptor (NMDAR) GluN2B subunit expression following anesthesia, which was...

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Detalles Bibliográficos
Autores principales: LI, LUNXU, LI, ZHENGQIAN, CAO, YIYUN, FAN, DONGSHENG, CHUI, DEHUA, GUO, XIANGYANG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906658/
https://www.ncbi.nlm.nih.gov/pubmed/27347033
http://dx.doi.org/10.3892/etm.2016.3306