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Treatment with rGDF11 does not improve the dystrophic muscle pathology of mdx mice

BACKGROUND: Duchenne muscular dystrophy (DMD) is an inherited lethal muscle wasting disease characterized by cycles of degeneration and regeneration, with no effective therapy. Growth differentiation factor 11 (GDF11), a member of the TGF-β superfamily and myostatin homologous, has been reported to...

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Detalles Bibliográficos
Autores principales: Rinaldi, Fabrizio, Zhang, Yu, Mondragon-Gonzalez, Ricardo, Harvey, Jeffrey, Perlingeiro, Rita C. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906773/
https://www.ncbi.nlm.nih.gov/pubmed/27303621
http://dx.doi.org/10.1186/s13395-016-0092-8