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Intronic cleavage and polyadenylation regulates gene expression during DNA damage response through U1 snRNA

The DNA damage response involves coordinated control of gene expression and DNA repair. Using deep sequencing, we found widespread changes of alternative cleavage and polyadenylation site usage on ultraviolet-treatment in mammalian cells. Alternative cleavage and polyadenylation regulation in the 3ʹ...

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Detalles Bibliográficos
Autores principales: Devany, Emral, Park, Ji Yeon, Murphy, Michael R, Zakusilo, George, Baquero, Jorge, Zhang, Xiaokan, Hoque, Mainul, Tian, Bin, Kleiman, Frida E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906801/
https://www.ncbi.nlm.nih.gov/pubmed/27462460
http://dx.doi.org/10.1038/celldisc.2016.13