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Intronic cleavage and polyadenylation regulates gene expression during DNA damage response through U1 snRNA
The DNA damage response involves coordinated control of gene expression and DNA repair. Using deep sequencing, we found widespread changes of alternative cleavage and polyadenylation site usage on ultraviolet-treatment in mammalian cells. Alternative cleavage and polyadenylation regulation in the 3ʹ...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906801/ https://www.ncbi.nlm.nih.gov/pubmed/27462460 http://dx.doi.org/10.1038/celldisc.2016.13 |