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Vitamin K antagonist use: evidence of the difficulty of achieving and maintaining target INR range and subsequent consequences

Vitamin K antagonists (VKAs) are effective oral anticoagulants that are titrated to a narrow therapeutic international normalized ratio (INR) range. We reviewed published literature assessing the impact of INR stability - getting into and staying in target INR range - on outcomes including thromboti...

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Detalles Bibliográficos
Autores principales: Schein, Jeff R., White, C. Michael, Nelson, Winnie W., Kluger, Jeffrey, Mearns, Elizabeth S., Coleman, Craig I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906845/
https://www.ncbi.nlm.nih.gov/pubmed/27303213
http://dx.doi.org/10.1186/s12959-016-0088-y