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Low-dose oral cholecalciferol is associated with higher numbers of Helios(+) and total Tregs than oral calcitriol in renal allograft recipients: an observational study

BACKGROUND: Regulatory T cells (Tregs) are a cornerstone of graft acceptance. High numbers of Tregs are associated with better long-term graft survival. Recently, Vitamin D was suggested as an immunomodulator, in addition to its classical role in calcium metabolism. Vitamin D modulates Tregs and mig...

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Detalles Bibliográficos
Autores principales: Aly, Mostafa G., Trojan, Karina, Weimer, Rolf, Morath, Christian, Opelz, Gerhard, Tohamy, Mohammed A., Daniel, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906900/
https://www.ncbi.nlm.nih.gov/pubmed/27296673
http://dx.doi.org/10.1186/s40360-016-0066-9