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An autoradiographic evaluation of AV-1451 Tau PET in dementia

BACKGROUND: It is essential to determine the specificity of AV-1451 PET for tau in brain imaging by using pathological comparisons. We performed autoradiography in autopsy-confirmed Alzheimer disease and other neurodegenerative disorders to evaluate the specificity of AV-1451 binding for tau aggrega...

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Detalles Bibliográficos
Autores principales: Lowe, Val J., Curran, Geoffry, Fang, Ping, Liesinger, Amanda M., Josephs, Keith A., Parisi, Joseph E., Kantarci, Kejal, Boeve, Bradley F., Pandey, Mukesh K., Bruinsma, Tyler, Knopman, David S., Jones, David T., Petrucelli, Leonard, Cook, Casey N., Graff-Radford, Neill R., Dickson, Dennis W., Petersen, Ronald C., Jack, Clifford R., Murray, Melissa E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906968/
https://www.ncbi.nlm.nih.gov/pubmed/27296779
http://dx.doi.org/10.1186/s40478-016-0315-6