Eosinophils enhance WNT-5a and TGF-β(1) genes expression in airway smooth muscle cells and promote their proliferation by increased extracellular matrix proteins production in asthma

BACKGROUND: Recent studies have suggested that eosinophils may have a direct effect on airway smooth muscle cells (ASMC), causing their proliferation in patients with asthma, but the precise mechanism of the interaction between these cells remains unknown. We propose that changes in Wnt signaling ac...

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Detalles Bibliográficos
Autores principales: Januskevicius, Andrius, Vaitkiene, Simona, Gosens, Reinoud, Janulaityte, Ieva, Hoppenot, Deimante, Sakalauskas, Raimundas, Malakauskas, Kestutis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906992/
https://www.ncbi.nlm.nih.gov/pubmed/27297409
http://dx.doi.org/10.1186/s12890-016-0254-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906992/
https://www.ncbi.nlm.nih.gov/pubmed/27297409
http://dx.doi.org/10.1186/s12890-016-0254-9

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