Evolution and expression of the phosphodiesterase 6 genes unveils vertebrate novelty to control photosensitivity

BACKGROUND: Phosphodiesterase 6 (PDE6) is a protein complex that hydrolyses cGMP and acts as the effector of the vertebrate phototransduction cascade. The PDE6 holoenzyme consists of catalytic and inhibitory subunits belonging to two unrelated gene families. Rods and cones express distinct genes fro...

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Detalles Bibliográficos
Autores principales: Lagman, David, Franzén, Ilkin E., Eggert, Joel, Larhammar, Dan, Abalo, Xesús M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906994/
https://www.ncbi.nlm.nih.gov/pubmed/27296292
http://dx.doi.org/10.1186/s12862-016-0695-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906994/
https://www.ncbi.nlm.nih.gov/pubmed/27296292
http://dx.doi.org/10.1186/s12862-016-0695-z

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