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Evolution and expression of the phosphodiesterase 6 genes unveils vertebrate novelty to control photosensitivity
BACKGROUND: Phosphodiesterase 6 (PDE6) is a protein complex that hydrolyses cGMP and acts as the effector of the vertebrate phototransduction cascade. The PDE6 holoenzyme consists of catalytic and inhibitory subunits belonging to two unrelated gene families. Rods and cones express distinct genes fro...
Autores principales: | Lagman, David, Franzén, Ilkin E., Eggert, Joel, Larhammar, Dan, Abalo, Xesús M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906994/ https://www.ncbi.nlm.nih.gov/pubmed/27296292 http://dx.doi.org/10.1186/s12862-016-0695-z |
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