Outlier analysis of functional genomic profiles enriches for oncology targets and enables precision medicine

BACKGROUND: Genome-scale functional genomic screens across large cell line panels provide a rich resource for discovering tumor vulnerabilities that can lead to the next generation of targeted therapies. Their data analysis typically has focused on identifying genes whose knockdown enhances response...

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Detalles Bibliográficos
Autores principales: Zhu, Zhou, Ihle, Nathan T., Rejto, Paul A., Zarrinkar, Patrick P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907009/
https://www.ncbi.nlm.nih.gov/pubmed/27296290
http://dx.doi.org/10.1186/s12864-016-2807-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907009/
https://www.ncbi.nlm.nih.gov/pubmed/27296290
http://dx.doi.org/10.1186/s12864-016-2807-y

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