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Outlier analysis of functional genomic profiles enriches for oncology targets and enables precision medicine
BACKGROUND: Genome-scale functional genomic screens across large cell line panels provide a rich resource for discovering tumor vulnerabilities that can lead to the next generation of targeted therapies. Their data analysis typically has focused on identifying genes whose knockdown enhances response...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907009/ https://www.ncbi.nlm.nih.gov/pubmed/27296290 http://dx.doi.org/10.1186/s12864-016-2807-y |