Mast cell depletion in the preclinical phase of collagen-induced arthritis reduces clinical outcome by lowering the inflammatory cytokine profile

BACKGROUND: Rheumatoid arthritis (RA) is a multifactorial autoimmune disease, which is characterized by inflammation of synovial joints leading to the destruction of cartilage and bone. Infiltrating mast cells can be found within the inflamed synovial tissue, however their role in disease pathogenes...

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Detalles Bibliográficos
Autores principales: van der Velden, Daniël, Lagraauw, H. Maxime, Wezel, Anouk, Launay, Pierre, Kuiper, Johan, Huizinga, Tom W. J., Toes, René E. M., Bot, Ilze, Stoop, Jeroen N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907027/
https://www.ncbi.nlm.nih.gov/pubmed/27296719
http://dx.doi.org/10.1186/s13075-016-1036-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907027/
https://www.ncbi.nlm.nih.gov/pubmed/27296719
http://dx.doi.org/10.1186/s13075-016-1036-8

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