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SUMO Ligase Protein Inhibitor of Activated STAT1 (PIAS1) Is a Constituent Promyelocytic Leukemia Nuclear Body Protein That Contributes to the Intrinsic Antiviral Immune Response to Herpes Simplex Virus 1

Aspects of intrinsic antiviral immunity are mediated by promyelocytic leukemia nuclear body (PML-NB) constituent proteins. During herpesvirus infection, these antiviral proteins are independently recruited to nuclear domains that contain infecting viral genomes to cooperatively promote viral genome...

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Detalles Bibliográficos
Autores principales: Brown, James R., Conn, Kristen L., Wasson, Peter, Charman, Matthew, Tong, Lily, Grant, Kyle, McFarlane, Steven, Boutell, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907222/
https://www.ncbi.nlm.nih.gov/pubmed/27099310
http://dx.doi.org/10.1128/JVI.00426-16