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Complexities of X chromosome inactivation status in female human induced pluripotent stem cells—a brief review and scientific update for autism research

Induced pluripotent stem cells (iPSCs) allow researchers to make customized patient-derived cell lines by reprogramming noninvasively retrieved somatic cells. These cell lines have the potential to faithfully represent an individual’s genetic background; therefore, in the absence of available human...

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Detalles Bibliográficos
Autores principales: Dandulakis, Mary G., Meganathan, Kesavan, Kroll, Kristen L., Bonni, Azad, Constantino, John N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907282/
https://www.ncbi.nlm.nih.gov/pubmed/27303449
http://dx.doi.org/10.1186/s11689-016-9155-8