Responder Interferon λ Genotypes Are Associated With Higher Risk of Liver Fibrosis in HIV–Hepatitis C Virus Coinfection

Background. Liver fibrosis progresses faster in individuals coinfected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV). Interferon λ3 (IFN-λ3) has both antiviral and proinflammatory properties. Genotypes at IFNL single-nucleotide proteins (SNPs; rs12979860CC and rs8099917TT) are...

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Detalles Bibliográficos
Autores principales: Moqueet, Nasheed, Cooper, Curtis, Gill, John, Hull, Mark, Platt, Robert W., Klein, Marina B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907413/
https://www.ncbi.nlm.nih.gov/pubmed/26984148
http://dx.doi.org/10.1093/infdis/jiw088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907413/
https://www.ncbi.nlm.nih.gov/pubmed/26984148
http://dx.doi.org/10.1093/infdis/jiw088

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