Erythropoietin Slows Photoreceptor Cell Death in a Mouse Model of Autosomal Dominant Retinitis Pigmentosa

PURPOSE: To test the efficacy of systemic gene delivery of a mutant form of erythropoietin (EPO-R76E) that has attenuated erythropoietic activity, in a mouse model of autosomal dominant retinitis pigmentosa. METHODS: Ten-day old mice carrying one copy of human rhodopsin with the P23H mutation and bo...

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Detalles Bibliográficos
Autores principales: Rex, Tonia S., Kasmala, Lorraine, Bond, Wesley S., de Lucas Cerrillo, Ana M., Wynn, Kristi, Lewin, Alfred S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907422/
https://www.ncbi.nlm.nih.gov/pubmed/27299810
http://dx.doi.org/10.1371/journal.pone.0157411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907422/
https://www.ncbi.nlm.nih.gov/pubmed/27299810
http://dx.doi.org/10.1371/journal.pone.0157411

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