Phosphodiesterase Type 5 Inhibitors and Risk of Malignant Melanoma: Matched Cohort Study Using Primary Care Data from the UK Clinical Practice Research Datalink

BACKGROUND: Laboratory evidence suggests that reduced phosphodiesterase type 5 (PDE5) expression increases the invasiveness of melanoma cells; hence, pharmacological inhibition of PDE5 could affect melanoma risk. Two major epidemiological studies have investigated this and come to differing conclusi...

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Detalles Bibliográficos
Autores principales: Matthews, Anthony, Langan, Sinéad M., Douglas, Ian J., Smeeth, Liam, Bhaskaran, Krishnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907438/
https://www.ncbi.nlm.nih.gov/pubmed/27299522
http://dx.doi.org/10.1371/journal.pmed.1002037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907438/
https://www.ncbi.nlm.nih.gov/pubmed/27299522
http://dx.doi.org/10.1371/journal.pmed.1002037

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