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Phosphodiesterase Type 5 Inhibitors and Risk of Malignant Melanoma: Matched Cohort Study Using Primary Care Data from the UK Clinical Practice Research Datalink

BACKGROUND: Laboratory evidence suggests that reduced phosphodiesterase type 5 (PDE5) expression increases the invasiveness of melanoma cells; hence, pharmacological inhibition of PDE5 could affect melanoma risk. Two major epidemiological studies have investigated this and come to differing conclusi...

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Detalles Bibliográficos
Autores principales:	Matthews, Anthony, Langan, Sinéad M., Douglas, Ian J., Smeeth, Liam, Bhaskaran, Krishnan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907438/ https://www.ncbi.nlm.nih.gov/pubmed/27299522 http://dx.doi.org/10.1371/journal.pmed.1002037

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