ALIX Regulates the Ubiquitin-Independent Lysosomal Sorting of the P2Y(1) Purinergic Receptor via a YPX(3)L Motif

Endocytic sorting and lysosomal degradation are integral to the regulation of G protein-coupled receptor (GPCR) function. Upon ligand binding, classical GPCRs are activated, internalized and recycled or sorted to lysosomes for degradation, a process that requires receptor ubiquitination. However, re...

Descripción completa

Detalles Bibliográficos
Autores principales: Dores, Michael R., Grimsey, Neil J., Mendez, Francisco, Trejo, JoAnn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907476/
https://www.ncbi.nlm.nih.gov/pubmed/27301021
http://dx.doi.org/10.1371/journal.pone.0157587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907476/
https://www.ncbi.nlm.nih.gov/pubmed/27301021
http://dx.doi.org/10.1371/journal.pone.0157587

Ejemplares similares