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New Insight into Metal Ion-Driven Catalysis of Nucleic Acids by Influenza PA-Nter

PA subunit of influenza RNA-dependent RNA polymerase deserves constantly increasing attention due to its essential role in influenza life cycle. N-terminal domain of PA (PA-Nter) harbors endonuclease activity, which is indispensable in viral transcription and replication. Interestingly, existing lit...

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Detalles Bibliográficos
Autores principales: Kotlarek, Daria, Worch, Remigiusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907508/
https://www.ncbi.nlm.nih.gov/pubmed/27300442
http://dx.doi.org/10.1371/journal.pone.0156972