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Mitochondrial DNA Rearrangement Spectrum in Brain Tissue of Alzheimer’s Disease: Analysis of 13 Cases

BACKGROUND: Mitochondrial dysfunction may play a central role in the pathologic process of Alzheimer’s disease (AD), but there is still a scarcity of data that directly links the pathology of AD with the alteration of mitochondrial DNA. This study aimed to provide a comprehensive assessment of mtDNA...

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Detalles Bibliográficos
Autores principales: Chen, Yucai, Liu, Changsheng, Parker, William Davis, Chen, Hongyi, Beach, Thomas G., Liu, Xinhua, Serrano, Geidy E., Lu, Yanfen, Huang, Jianjun, Yang, Kunfang, Wang, Chunmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907522/
https://www.ncbi.nlm.nih.gov/pubmed/27299301
http://dx.doi.org/10.1371/journal.pone.0154582