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Microglia regulate hippocampal neurogenesis during chronic neurodegeneration
Neurogenesis is altered in neurodegenerative disorders, partly regulated by inflammatory factors. We have investigated whether microglia, the innate immune brain cells, regulate hippocampal neurogenesis in neurodegeneration. Using the ME7 model of prion disease we applied gain- or loss-of CSF1R func...
Autores principales: | De Lucia, Chiara, Rinchon, Adeline, Olmos-Alonso, Adrian, Riecken, Kristoffer, Fehse, Boris, Boche, Delphine, Perry, V. Hugh, Gomez-Nicola, Diego |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907582/ https://www.ncbi.nlm.nih.gov/pubmed/26541819 http://dx.doi.org/10.1016/j.bbi.2015.11.001 |
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