A Response Surface Model Exploration of Dosing Strategies in Gastrointestinal Endoscopies Using Midazolam and Opioids

Classical midazolam–opioid combination for gastrointestinal endoscopy sedation has been adopted for decades. Dosing regimens have been studied but most require fixed dosing intervals. We intend to use a sophisticated pharmacodynamic tool, response surface model (RSM), to simulate sedation using diff...

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Detalles Bibliográficos
Autores principales: Liou, Jing-Yang, Ting, Chien-Kun, Hou, Ming-Chih, Tsou, Mei-Yung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
3300
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907643/
https://www.ncbi.nlm.nih.gov/pubmed/27281065
http://dx.doi.org/10.1097/MD.0000000000003520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907643/
https://www.ncbi.nlm.nih.gov/pubmed/27281065
http://dx.doi.org/10.1097/MD.0000000000003520

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