Two-way communication between SecY and SecA suggests a Brownian ratchet mechanism for protein translocation

The essential process of protein secretion is achieved by the ubiquitous Sec machinery. In prokaryotes, the drive for translocation comes from ATP hydrolysis by the cytosolic motor-protein SecA, in concert with the proton motive force (PMF). However, the mechanism through which ATP hydrolysis by Sec...

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Detalles Bibliográficos
Autores principales: Allen, William John, Corey, Robin Adam, Oatley, Peter, Sessions, Richard Barry, Baldwin, Steve A, Radford, Sheena E, Tuma, Roman, Collinson, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907695/
https://www.ncbi.nlm.nih.gov/pubmed/27183269
http://dx.doi.org/10.7554/eLife.15598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907695/
https://www.ncbi.nlm.nih.gov/pubmed/27183269
http://dx.doi.org/10.7554/eLife.15598

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