Design and statistical modeling of mannose-decorated dapsone-containing nanoparticles as a strategy of targeting intestinal M-cells

The aim of the present work was to develop and optimize surface-functionalized solid lipid nanoparticles (SLNs) for improvement of the therapeutic index of dapsone (DAP), with the application of a design of experiments. The formulation was designed to target intestinal microfold (M-cells) as a strat...

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Detalles Bibliográficos
Autores principales: Vieira, Alexandre CC, Chaves, Luíse L, Pinheiro, Marina, Ferreira, Domingos, Sarmento, Bruno, Reis, Salette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907709/
https://www.ncbi.nlm.nih.gov/pubmed/27354792
http://dx.doi.org/10.2147/IJN.S104908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907709/
https://www.ncbi.nlm.nih.gov/pubmed/27354792
http://dx.doi.org/10.2147/IJN.S104908

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