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Delivery of dexamethasone from bioactive nanofiber matrices stimulates odontogenesis of human dental pulp cells through integrin/BMP/mTOR signaling pathways

Therapeutically relevant design of scaffolds is of special importance in the repair and regeneration of tissues including dentin and pulp. Here we exploit nanofiber matrices that incorporate bioactive glass nanoparticles (BGNs) and deliver the odontogenic drug dexamethasone (DEX) to stimulate the od...

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Detalles Bibliográficos
Autores principales: Lim, Hyun-Chang, Nam, Ok Hyung, Kim, Mi-joo, El-Fiqi, Ahmed, Yun, Hyung-Mun, Lee, Yoo-Mi, Jin, Guang-Zhen, Lee, Hae-Hyoung, Kim, Hae-Won, Kim, Eun-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907710/
https://www.ncbi.nlm.nih.gov/pubmed/27354790
http://dx.doi.org/10.2147/IJN.S97846