In vivo targeted gene delivery to peripheral neurons mediated by neurotropic poly(ethylene imine)-based nanoparticles

A major challenge in neuronal gene therapy is to achieve safe, efficient, and minimally invasive transgene delivery to neurons. In this study, we report the use of a nonviral neurotropic poly(ethylene imine)-based nanoparticle that is capable of mediating neuron-specific transfection upon a subcutan...

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Detalles Bibliográficos
Autores principales: Lopes, Cátia DF, Oliveira, Hugo, Estevão, Inês, Pires, Liliana Raquel, Pêgo, Ana Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907712/
https://www.ncbi.nlm.nih.gov/pubmed/27354797
http://dx.doi.org/10.2147/IJN.S104374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907712/
https://www.ncbi.nlm.nih.gov/pubmed/27354797
http://dx.doi.org/10.2147/IJN.S104374

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