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In vivo targeted gene delivery to peripheral neurons mediated by neurotropic poly(ethylene imine)-based nanoparticles
A major challenge in neuronal gene therapy is to achieve safe, efficient, and minimally invasive transgene delivery to neurons. In this study, we report the use of a nonviral neurotropic poly(ethylene imine)-based nanoparticle that is capable of mediating neuron-specific transfection upon a subcutan...
Autores principales: | Lopes, Cátia DF, Oliveira, Hugo, Estevão, Inês, Pires, Liliana Raquel, Pêgo, Ana Paula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907712/ https://www.ncbi.nlm.nih.gov/pubmed/27354797 http://dx.doi.org/10.2147/IJN.S104374 |
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