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Elimination of the biphasic pharmacodynamics of 15d-PGJ2 by controlling its release from a nanoemulsion
15-Deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2) has a dual action of stimulating anti-inflammation and anti-proliferation when exogenously administered at high doses. However, at lower doses, it can be toxic inducing opposite actions, ie, stimulation of both inflammation and cell proliferation. This bip...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907719/ https://www.ncbi.nlm.nih.gov/pubmed/27354798 http://dx.doi.org/10.2147/IJN.S106297 |