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Quiescent Saccharomyces cerevisiae forms telomere hyperclusters at the nuclear membrane vicinity through a multifaceted mechanism involving Esc1, the Sir complex, and chromatin condensation

Like other eukaryotes, Saccharomyces cerevisiae spatially organizes its chromosomes within the nucleus. In G(1) phase, the yeast’s 32 telomeres are clustered into 6–10 foci that dynamically interact with the nuclear membrane. Here we show that, when cells leave the division cycle and enter quiescenc...

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Detalles Bibliográficos
Autores principales: Laporte, Damien, Courtout, Fabien, Tollis, Sylvain, Sagot, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907721/
https://www.ncbi.nlm.nih.gov/pubmed/27122604
http://dx.doi.org/10.1091/mbc.E16-01-0069