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Excess centrosomes perturb dynamic endothelial cell repolarization during blood vessel formation

Blood vessel formation requires dynamic movements of endothelial cells (ECs) within sprouts. The cytoskeleton regulates migratory polarity, and centrosomes organize the microtubule cytoskeleton. However, it is not well understood how excess centrosomes, commonly found in tumor stromal cells, affect...

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Detalles Bibliográficos
Autores principales: Kushner, Erich J., Ferro, Luke S., Yu, Zhixian, Bautch, Victoria L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907724/
https://www.ncbi.nlm.nih.gov/pubmed/27099371
http://dx.doi.org/10.1091/mbc.E15-09-0645