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Excess centrosomes perturb dynamic endothelial cell repolarization during blood vessel formation
Blood vessel formation requires dynamic movements of endothelial cells (ECs) within sprouts. The cytoskeleton regulates migratory polarity, and centrosomes organize the microtubule cytoskeleton. However, it is not well understood how excess centrosomes, commonly found in tumor stromal cells, affect...
Autores principales: | Kushner, Erich J., Ferro, Luke S., Yu, Zhixian, Bautch, Victoria L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907724/ https://www.ncbi.nlm.nih.gov/pubmed/27099371 http://dx.doi.org/10.1091/mbc.E15-09-0645 |
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