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GPR30 decreases with vascular aging and promotes vascular smooth muscle cells maintaining differentiated phenotype and suppressing migration via activation of ERK1/2

Estrogen receptors, including classic nuclear receptors ERα, ERβ, and membrane receptor GPR30, are expressed in vascular tissues and exert protective actions in vascular diseases. But the expression pattern and functional roles of GPR30 in vascular smooth muscle cells (VSMCs) remain unclear. In this...

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Detalles Bibliográficos
Autores principales: Huang, Fang, Yin, Jianguo, Li, Keyu, Li, Ying, Qi, Heng, Fang, Li, Yuan, Cong, Liu, Weiwei, Wang, Min, Li, Xiangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907733/
https://www.ncbi.nlm.nih.gov/pubmed/27354813
http://dx.doi.org/10.2147/OTT.S104972