Cargando…

GPR30 decreases with vascular aging and promotes vascular smooth muscle cells maintaining differentiated phenotype and suppressing migration via activation of ERK1/2

Estrogen receptors, including classic nuclear receptors ERα, ERβ, and membrane receptor GPR30, are expressed in vascular tissues and exert protective actions in vascular diseases. But the expression pattern and functional roles of GPR30 in vascular smooth muscle cells (VSMCs) remain unclear. In this...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Fang, Yin, Jianguo, Li, Keyu, Li, Ying, Qi, Heng, Fang, Li, Yuan, Cong, Liu, Weiwei, Wang, Min, Li, Xiangping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907733/ https://www.ncbi.nlm.nih.gov/pubmed/27354813 http://dx.doi.org/10.2147/OTT.S104972

Ejemplares similares

GPR30 Promotes the Phenotypic Switching of Vascular Smooth Muscle Cells via Activating the AKT and ERK Pathways
por: Zha, Binshan, et al.
Publicado: (2020)

DFMG reverses proliferation and migration of vascular smooth muscle cells induced by co-culture with injured vascular endothelial cells via suppression of the TLR4-mediated signaling pathway
por: Cong, Li, et al.
Publicado: (2018)

Permanently proliferating rat vascular smooth muscle cell with maintained expression of smooth muscle characteristics, including actin of the vascular smooth muscle type
Publicado: (1980)

Improvement of Vascular Function by Acute and Chronic Treatment with the GPR30 Agonist G1 in Experimental Diabetes Mellitus
por: Li, Zi-lin, et al.
Publicado: (2012)

Luteolin Ameliorates Hypertensive Vascular Remodeling through Inhibiting the Proliferation and Migration of Vascular Smooth Muscle Cells
por: Su, Jie, et al.
Publicado: (2015)

Phenotypic plasticity of vascular smooth muscle cells in vascular calcification: Role of mitochondria
por: Liu, Yan Zhong, et al.
Publicado: (2022)

Emerging regulators of vascular smooth muscle cell migration
por: Afewerki, TecLino, et al.
Publicado: (2019)

Inhibitory Effects and Mechanisms of Luteolin on Proliferation and Migration of Vascular Smooth Muscle Cells
por: Jiang, Dehua, et al.
Publicado: (2013)

GPR109A and Vascular Inflammation
por: Chai, Joshua T., et al.
Publicado: (2013)

Endoglin Mediates Vascular Maturation by Promoting Vascular Smooth Muscle Cell Migration and Spreading
por: Tian, Hongyu, et al.
Publicado: (2017)

Heat shock protein 60 stimulates the migration of vascular smooth muscle cells via Toll-like receptor 4 and ERK MAPK activation
por: Zhao, Ying, et al.
Publicado: (2015)

Metformin decreases hyaluronan synthesis by vascular smooth muscle cells
por: Sainio, Annele, et al.
Publicado: (2020)

Decorin Mimic Inhibits Vascular Smooth Muscle Proliferation and Migration
por: Scott, Rebecca A., et al.
Publicado: (2013)

The role of Exo70 in vascular smooth muscle cell migration
por: Ma, Wenqing, et al.
Publicado: (2016)

BACH1 deficiency prevents neointima formation and maintains the differentiated phenotype of vascular smooth muscle cells by regulating chromatin accessibility
por: Guo, Jieyu, et al.
Publicado: (2023)

Bone Morphogenetic Protein‐2 Decreases MicroRNA‐30b and MicroRNA‐30c to Promote Vascular Smooth Muscle Cell Calcification
por: Balderman, Joshua A. F., et al.
Publicado: (2012)

Ghrelin Attenuates the Osteoblastic Differentiation of Vascular Smooth Muscle Cells through the ERK Pathway
por: Liang, Qiu-Hua, et al.
Publicado: (2012)

Chronic BDE-47 Exposure Aggravates Malignant Phenotypes and Chemoresistance by Activating ERK Through ERα and GPR30 in Endometrial Carcinoma
por: Zhang, Fan, et al.
Publicado: (2019)

Docosahexaenoic acid inhibits vascular smooth muscle cell migration and proliferation by decreasing microRNA-155 expression levels
por: Yin, Xiaoliang, et al.
Publicado: (2020)

Hypomethylation of Rnase6 Promoter Enhances Proliferation and Migration of Murine Aortic Vascular Smooth Muscle Cells and Aggravates Atherosclerosis in Mice
por: Fang, YongPeng, et al.
Publicado: (2021)

C1q/TNF‐related protein 4 mediates proliferation and migration of vascular smooth muscle cells during vascular remodelling
por: Liu, Jingying, et al.
Publicado: (2023)

LncRNA BANCR facilitates vascular smooth muscle cell proliferation and migration through JNK pathway
por: Li, He, et al.
Publicado: (2017)

Glossogyne tenuifolia Attenuates Proliferation and Migration of Vascular Smooth Muscle Cells
por: Hsuan, Chin-Feng, et al.
Publicado: (2020)

The FAT1 Cadherin Drives Vascular Smooth Muscle Cell Migration
por: Riascos-Bernal, Dario F., et al.
Publicado: (2023)

Mechanisms of vascular smooth muscle cell investment and phenotypic diversification in vascular diseases
por: Worssam, Matthew D., et al.
Publicado: (2021)

How vascular smooth muscle cell phenotype switching contributes to vascular disease
por: Cao, Genmao, et al.
Publicado: (2022)

Large-conductance Ca(2 +)-activated K(+) channel β1-subunit maintains the contractile phenotype of vascular smooth muscle cells
por: Wang, Meili, et al.
Publicado: (2022)

BMP-2 Overexpression Augments Vascular Smooth Muscle Cell Motility by Upregulating Myosin Va via Erk Signaling
por: Zhang, Ming, et al.
Publicado: (2014)

Rho/ROCK Signal Cascade Mediates Asymmetric Dimethylarginine-Induced Vascular Smooth Muscle Cells Migration and Phenotype Change
por: Zhou, Yi-ming, et al.
Publicado: (2014)

Plin5 inhibits proliferation and migration of vascular smooth muscle cell through interacting with PGC-1α following vascular injury
por: Gan, Xueqing, et al.
Publicado: (2022)

PRDX2 Protects Against Atherosclerosis by Regulating the Phenotype and Function of the Vascular Smooth Muscle Cell
por: Li, Jing, et al.
Publicado: (2021)

Curcumin-mediated Photodynamic Therapy Inhibits the Phenotypic Transformation, Migration, and Foaming of Oxidized Low-density Lipoprotein-treated Vascular Smooth Muscle Cells by Promoting Autophagy
por: Wang, Gailan, et al.
Publicado: (2021)

Tanshinone IIA inhibits AGEs-induced proliferation and migration of cultured vascular smooth muscle cells by suppressing ERK1/2 MAPK signaling
por: Lu, Ming, et al.
Publicado: (2018)

Fluvastatin inhibits AGE-induced cell proliferation and migration via an ERK5-dependent Nrf2 pathway in vascular smooth muscle cells
por: Hwang, Ae-Rang, et al.
Publicado: (2017)

HIX003209 promotes vascular smooth muscle cell migration and proliferation through modulating miR-6089
por: Shi, Xiaofeng, et al.
Publicado: (2020)

Age decreases mitochondrial motility and increases mitochondrial size in vascular smooth muscle
por: Chalmers, Susan, et al.
Publicado: (2016)

Expression of Long Noncoding RNA LIPCAR Promotes Cell Proliferation, Cell Migration, and Change in Phenotype of Vascular Smooth Muscle Cells
por: Wang, Xiaoyan, et al.
Publicado: (2019)

Senescence in Vascular Smooth Muscle Cells and Atherosclerosis
por: Zha, Yiwen, et al.
Publicado: (2022)

RGS5 Attenuates Baseline Activity of ERK1/2 and Promotes Growth Arrest of Vascular Smooth Muscle Cells
por: Demirel, Eda, et al.
Publicado: (2021)

Macrophage Foam Cell–Derived Extracellular Vesicles Promote Vascular Smooth Muscle Cell Migration and Adhesion
por: Niu, Chenguang, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_u5617jt5g99ceus2b63giir0et