Two Small RNAs Conserved in Enterobacteriaceae Provide Intrinsic Resistance to Antibiotics Targeting the Cell Wall Biosynthesis Enzyme Glucosamine-6-Phosphate Synthase

Formation of glucosamine-6-phosphate (GlcN6P) by enzyme GlcN6P synthase (GlmS) represents the first step in bacterial cell envelope synthesis. In Escherichia coli, expression of glmS is controlled by small RNAs (sRNAs) GlmY and GlmZ. GlmZ activates the glmS mRNA by base-pairing. When not required, G...

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Detalles Bibliográficos
Autores principales: Khan, Muna A., Göpel, Yvonne, Milewski, Slawomir, Görke, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908143/
https://www.ncbi.nlm.nih.gov/pubmed/27379045
http://dx.doi.org/10.3389/fmicb.2016.00908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908143/
https://www.ncbi.nlm.nih.gov/pubmed/27379045
http://dx.doi.org/10.3389/fmicb.2016.00908

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