RNA Interference Prevents Autosomal-Dominant Hearing Loss

Hearing impairment is the most common sensory deficit. It is frequently caused by the expression of an allele carrying a single dominant missense mutation. Herein, we show that a single intracochlear injection of an artificial microRNA carried in a viral vector can slow progression of hearing loss f...

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Detalles Bibliográficos
Autores principales: Shibata, Seiji B., Ranum, Paul T., Moteki, Hideaki, Pan, Bifeng, Goodwin, Alexander T., Goodman, Shawn S., Abbas, Paul J., Holt, Jeffrey R., Smith, Richard J.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908151/
https://www.ncbi.nlm.nih.gov/pubmed/27236922
http://dx.doi.org/10.1016/j.ajhg.2016.03.028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908151/
https://www.ncbi.nlm.nih.gov/pubmed/27236922
http://dx.doi.org/10.1016/j.ajhg.2016.03.028

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