The acute and long‐term L‐DOPA effects are independent from changes in the activity of dorsal raphe serotonergic neurons in 6‐OHDA lesioned rats

BACKGROUND AND PURPOSE: L‐DOPA is still the most efficacious pharmacological treatment for Parkinson's disease. However, in the majority of patients receiving long‐term therapy with L‐DOPA, its efficacy is compromised by motor complications, notably L‐DOPA‐induced dyskinesia. Evidence suggests...

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Detalles Bibliográficos
Autores principales: Miguelez, C, Navailles, S, De Deurwaerdère, P, Ugedo, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Themed Section: Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908202/
https://www.ncbi.nlm.nih.gov/pubmed/26805402
http://dx.doi.org/10.1111/bph.13447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908202/
https://www.ncbi.nlm.nih.gov/pubmed/26805402
http://dx.doi.org/10.1111/bph.13447

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