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“Inflammaging” as a Druggable Target: A Senescence-Associated Secretory Phenotype—Centered View of Type 2 Diabetes

Aging is a complex phenomenon driven by a variety of molecular alterations. A relevant feature of aging is chronic low-grade inflammation, termed “inflammaging.” In type 2 diabetes mellitus (T2DM), many elements of aging appear earlier or are overrepresented, including consistent inflammaging. T2DM...

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Detalles Bibliográficos
Autores principales: Prattichizzo, Francesco, De Nigris, Valeria, La Sala, Lucia, Procopio, Antonio Domenico, Olivieri, Fabiola, Ceriello, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908264/
https://www.ncbi.nlm.nih.gov/pubmed/27340505
http://dx.doi.org/10.1155/2016/1810327