A Fusion Protein Consisting of the Vaccine Adjuvant Monophosphoryl Lipid A and the Allergen Ovalbumin Boosts Allergen-Specific Th1, Th2, and Th17 Responses In Vitro

Background. The detoxified TLR4-ligand Monophosphoryl Lipid A (MPLA) is the first approved TLR-agonist used as adjuvant in licensed vaccines but has not yet been explored as part of conjugated vaccines. Objective. To investigate the immune-modulating properties of a fusion protein consisting of MPLA...

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Detalles Bibliográficos
Autores principales: Schülke, Stefan, Vogel, Lothar, Junker, Ann-Christine, Hanschmann, Kay-Martin, Flaczyk, Adam, Vieths, Stefan, Scheurer, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908266/
https://www.ncbi.nlm.nih.gov/pubmed/27340679
http://dx.doi.org/10.1155/2016/4156456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908266/
https://www.ncbi.nlm.nih.gov/pubmed/27340679
http://dx.doi.org/10.1155/2016/4156456

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