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A Fusion Protein Consisting of the Vaccine Adjuvant Monophosphoryl Lipid A and the Allergen Ovalbumin Boosts Allergen-Specific Th1, Th2, and Th17 Responses In Vitro

Background. The detoxified TLR4-ligand Monophosphoryl Lipid A (MPLA) is the first approved TLR-agonist used as adjuvant in licensed vaccines but has not yet been explored as part of conjugated vaccines. Objective. To investigate the immune-modulating properties of a fusion protein consisting of MPLA...

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Detalles Bibliográficos
Autores principales:	Schülke, Stefan, Vogel, Lothar, Junker, Ann-Christine, Hanschmann, Kay-Martin, Flaczyk, Adam, Vieths, Stefan, Scheurer, Stephan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908266/ https://www.ncbi.nlm.nih.gov/pubmed/27340679 http://dx.doi.org/10.1155/2016/4156456

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